Syracuse, NY 1972
National Tractor Trailer School's first students began training in June of 1971.  Originally established in Newburgh, New York, NTTS opened a Syracuse campus in January of 1972. Syracuse, NY proved to be more conducive to its mode of operation and more centrally located in freight lane. Therefore, in December of 1972 the schools merged into one campus located in Syracuse, NY. In November of 1977, NTTS moved to its present location in Liverpool, New York, and purchased the facility in May of 1981. NTTS received its initial accreditation from the Accrediting Commission of Career Schools and Colleges, in October of 1984, and subsequently became an eligible institution for Title IV funding in March of 1985. Since then, NTTS has been reaccredited four times.

Liverpool, NY  1987
In May of 1989, the school established a branch location in Blasdell, New York. In May of 1990, the Blasdell facility was moved to its current location and purchased by NTTS at 175 Katherine St, Buffalo, NY. In October 1990, the Buffalo location was accredited by the Accrediting Commission of Career Schools and Colleges as a branch location. Program offerings in Buffalo are essentially the same as at the Liverpool facility. Receiving its Commercial Drivers Course certification in July of 1998 from the Professional Truck Driver Institute, NTTS became part of a unique group of Professional Driver Training Schools in the United States and Canada. Since its inception, NTTS has remained under the same name and ownership.